HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Imidazole-4,5-dicarboxylic acid, 4,5-dimethyl ester → 1H-Imidazole-4,5-dimethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Imidazole-4,5-dicarboxylic acid, 4,5-dimethyl ester | HCID 76810 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1H-Imidazole-4,5-dimethanol | HCID 573629 | — |
Reaction Steps
Reflux dimethyl 4,5 imidazole dicarboxylate (1.8 g) in THF (tetrahydrofuran) with 2.5 equivalents of LAH lithium aluminum hydride). Neutralize with NH4Cl solution and filter. Concentrate the filtrate under vacumm and extract the product with ethanol. Remove the solvent, filtrate through alumina using a THF solvent to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04587241 |
| Source dataset | uspto-grants-1986_05 |
| ORD ID | ord-12483586f11b49f08bb683b241c74f50 |
| Source note | uspto-grants-1986_05 |