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HRID279846

反应详情

EQUATION

反应方程式

HRID 279846 的结构方程式

REACTANTS

反应物

1
结构：COC(=O)c1nc[nH]c1C(=O)OC
HCID76810

1H-Imidazole-4,5-dicarboxylic acid, dimethyl ester

C7H8N2O4

PRODUCTS

生成物

1
结构：OCc1nc[nH]c1CO
HCID573629

1H-Imidazole-4,5-dimethanol

C5H8N2O2

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

Reflux dimethyl 4,5 imidazole dicarboxylate (1.8 g) in THF (tetrahydrofuran) with 2.5 equivalents of LAH lithium aluminum hydride). Neutralize with NH4Cl solution and filter. Concentrate the filtrate under vacumm and extract the product with ethanol. Remove the solvent, filtrate through alumina using a THF solvent to give the title compound.

WORKUP

后处理

  1. filtrationNeutralize with NH4Cl solution and filter
  2. concentrationConcentrate the filtrate under vacumm
  3. extractionextract the product with ethanol
  4. customRemove the solvent, filtrate through alumina using a THF solvent