HCID 14203475, compound → 83112-44-1

HRID 279861Notes

Reaction equation

HRID 279861 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[O:11][CH2:12][C:13](=[O:16])[NH:14][N:15]=2)=[CH:6][CH:5]=1)([O-])=O>C(OCC)(=O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([C:10]2[O:11][CH2:12][C:13](=[O:16])[NH:14][N:15]=2)=[CH:8][CH:9]=1

Participants

4

Reactant 1

HCID 14203475HCID 14203475, compound

Product 1

HCID 1474284483112-44-1

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

A solution of 2-p-nitrophenyl-4H,6H-1,3,4-oxadiazin-5-one (Example 17; 2.2 g.) in ethyl acetate (250 ml.) was hydrogenated in the presence of a 5% palladium-on-charcoal catalyst at laboratory temperature and atmospheric pressure until 670 ml. of hydrogen had been absorbed. The mixture was filtered and the filtrate was evaporated to dryness. There was thus obtained as solid residue 2-p-aminophenyl-4H,6H-1,3,4-oxadiazin-5-one, m.p. 253°-255° C. (with decomposition).

Workup

  1. customof hydrogen had been absorbed
  2. filtrationThe mixture was filtered
  3. customthe filtrate was evaporated to dryness

Sources & evidence

ORD record
ord-25d3b7e5053a495092c033fd514f0c81
Source dataset
uspto-grants-1986_05
Patent number
US04587246

Reaction notes

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