Potassium Carbonate → HCID 13765577, compound

HRID 279918Notes

Reaction equation

HRID 279918 reaction equation
C(=O)([O-])[O-].[K+].[K+].[CH3:7][O:8][C:9](=[O:33])[C:10]1[CH:19]=[C:18]([O:20][C:21]2[CH:26]=[CH:25][C:24]([C:27]#[C:28][Si](C)(C)C)=[CH:23][CH:22]=2)[CH:17]=[C:12]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=1>CO.O1CCOCC1.O>[CH3:7][O:8][C:9](=[O:33])[C:10]1[CH:19]=[C:18]([O:20][C:21]2[CH:22]=[CH:23][C:24]([C:27]#[CH:28])=[CH:25][CH:26]=2)[CH:17]=[C:12]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=1

Participants

6

Reactant 2

HCID 11430Potassium CarbonateHCID 13765576HCID 13765576, compound

Product 1

HCID 13765577HCID 13765577, compoundYield 74%

Reagents, catalysts & solvents 3

HCID 887MethanolSolventHCID 962WaterSolventHCID 312751,4-DioxaneSolvent

Procedure

Powdered potassium carbonate (3.0 g) was added to a solution of dimethyl-5-(4-trimethylsilylethynylphenoxy)-isophthalate (5.0 g) in a mixture of methanol (80 ml) and dioxane (20 ml). A crystalline precipitate gradually formed upon stirring at ambient temperature for two hours. The reaction mixture was diluted with water (100 ml) and filtered to yield dimethyl-5-(4-ethynylphenoxy)isophthalate as a tan crystalline solid (3.0 g), m.p. 124'-125° C. Calculated for C18H14O5 : C, 69.68%; H, 4.55%. Found: C, 69.76%; H, 4.84%.

Workup

  1. customA crystalline precipitate gradually formed
  2. filtrationfiltered

Sources & evidence

ORD record
ord-bf37665a58e04b019cbd0475c0ddc07c
Source dataset
uspto-grants-1986_05
Patent number
US04587312

Reaction notes

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