Arabinosehydrazon → 1-deoxy-1-hydrazino-D-arabinitol

HRID 279932Notes

Reaction equation

HRID 279932 reaction equation
[CH:1](=[N:10][NH2:11])[C@H:2]([C@@H:4]([C@@H:6]([CH2:8][OH:9])[OH:7])[OH:5])[OH:3].[H][H]>C(O)C.O.[Pt]=O>[NH:10]([CH2:1][C@H:2]([C@@H:4]([C@@H:6]([CH2:8][OH:9])[OH:7])[OH:5])[OH:3])[NH2:11]

Participants

6

Reactant 2

HCID 86740783ArabinosehydrazonHCID 178418361HCID 178418361, compound

Product 1

HCID 538097401-deoxy-1-hydrazino-D-arabinitol

Reagents, catalysts & solvents 3

HCID 82844Platinum oxide (PtO)CatalystHCID 702EthanolSolventHCID 962WaterSolvent

Procedure

A 1.5 portion of D-arabinose hydrazone in 40 ml of ethanol and 20 ml of water was reduced with 200 mg of platinum oxide and hydrogen for 4 hours. The mixture was then filtered and the filtrate evaporated to dryness. The residue was dissolved in 40 ml of methanol and then evaporated to dryness, giving 1.24 g of 1-deoxy-1-hydrazino-D-arabinitol.

Workup

  1. filtrationThe mixture was then filtered
  2. customthe filtrate evaporated to dryness
  3. dissolutionThe residue was dissolved in 40 ml of methanol
  4. customevaporated to dryness

Sources & evidence

ORD record
ord-03dad06624e54c06b350ad757114f339
Source dataset
uspto-grants-1986_05
Patent number
US04587331

Reaction notes

Loading…