Methanol → HCID 135833480, compound

Participants

Reaction Steps

2,4-Diamino-6-n-butoxymethylpteridine-8-oxide. The product of Example 4A was reacted with guanidine in methanol according to the procedure described in Example 2 to give the title compound; mp >250°. UV: (0.1N HCl) λmax 252.5 (30,900), 282 (10,700), 343.5 (sh) (6,200), 356.5 (8,500), 369.5 (7,800) nm. NMR: δ (d6 -DMSO) 0.88 (t, 3H); 1.0-1.8 (m, 4H); 3.51 (t, 2H); 4.49 (s, 2H); 7.01 (br s, 2H); 7.75 (br s, 2H); 8.37 (s, 1H). IR: (KBr) 3700-2800, 1632, 1546, 1461, 1356, 1331, 1163, 1053, 978 cm-1. Anal. calcd. for C11H16N6O2 : C, 49.99; H, 6.10; N, 31.80. Found: C, 49.79; H, 6.11; N, 31.67.

Provenance & Evidence