HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 13478097, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Chloroquinazoline | HCID 74054 | — |
| Reactant | 1-[3-(4-Fluorophenoxy)propyl]piperazine | HCID 1873396 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 13478097 | HCID 13478097 | — |
Reaction Steps
2.5 g 2-Chloro-quinazoline, 3.8 g 1-[3-(4-fluorophenoxy)propyl]piperazine and 2.5 ml triethylamine in 15 ml isopropanol are stirred under reflux for 5 hours. The solvent is then evaporated in vacuo and the residue partitioned between water and methylene chloride. The organic phase is dried and evaporated. The residue is recrystallized from ethanol to yield the title compound, m.p. 126°-128° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04588725 |
| Source dataset | uspto-grants-1986_05 |
| ORD ID | ord-87f2de8023f14f53ac1b7ff2295fa747 |
| Source note | uspto-grants-1986_05 |