HuagongsheHuagongshe Chemistry Print Report · For research reference only
ethyl 4-(H-imidazo[1,5-a]pyridin-5-yl)benzoate → 5-(p-Carboxyphenyl)imidazo[1,5-a]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | ethyl 4-(H-imidazo[1,5-a]pyridin-5-yl)benzoate | HCID 13649431 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | 5-(p-Carboxyphenyl)imidazo[1,5-a]pyridine | HCID 13688224 | — |
Reaction Steps
A solution of 5-(p-ethoxycarbonylphenyl)-imidazo[1,5-a]pyridine (1.0 g) in 10 ml of ethanol and 10 ml of 1N sodium hydroxide is refluxed for 3 hours. The ethanol is evaporated. The aqueous phase is washed with ether, adjusted to pH=6 and the solid collected to yield 5-(p-carboxyphenyl)imidazo[1,5-a]pyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04588732 |
| Source dataset | uspto-grants-1986_05 |
| ORD ID | ord-7706647bea924dc8a726ba0ea88b11ee |
| Source note | uspto-grants-1986_05 |