Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosphorus oxychloride → 1,9-Dichloro-7-methoxy-4-nitroacridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosphorus oxychloride | HCID 24813 | — |
| 반응물 | 6-Chloro-2-(4-methoxyanilino)-3-nitrobenzoic acid | HCID 2778012 | — |
| 용매 | Chlorobenzene | HCID 7964 | — |
| 생성물 | 1,9-Dichloro-7-methoxy-4-nitroacridine | HCID 13588354 | — |
반응 단계
A stirred mixture of 12.9 of 6-chloro-2[(4-methoxyphenyl)amino]-3-nitrobenzoic acid, 25 ml of chlorobenzene and 50 ml of phosphorus oxychloride is heated to reflux temperature over a period of one hour, and held under reflux for 4.5 hours. The mixture is allowed to cool, the precipitate collected, providing the yellow title compound, mp 243-246 degrees after recrystallization from toluene.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04588730 |
| 출처 데이터셋 | uspto-grants-1986_05 |
| ORD ID | ord-6cfa0e4f8ded4377afde1258066fbcbb |
| 출처 메모 | uspto-grants-1986_05 |