反应详情

A stirred mixture of 12.9 of 6-chloro-2[(4-methoxyphenyl)amino]-3-nitrobenzoic acid, 25 ml of chlorobenzene and 50 ml of phosphorus oxychloride is heated to reflux temperature over a period of one hour, and held under reflux for 4.5 hours. The mixture is allowed to cool, the precipitate collected, providing the yellow title compound, mp 243-246 degrees after recrystallization from toluene.

1. temperatureis heated
2. temperatureto reflux temperature over a period of one hour
3. temperatureunder reflux for 4.5 hours
4. temperatureto cool
5. customthe precipitate collected