Hydrochloric Acid → HCID 178478602, compound

HRID 280421Notes

Reaction equation

HRID 280421 reaction equation
[NH2:1][C:2]1[C:6]([NH:7][CH2:8][CH2:9][CH2:10][O:11][C:12]2[CH:17]=[C:16]([CH2:18][N:19]3[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]3)[CH:15]=[CH:14][N:13]=2)=[N:5]S(=O)[N:3]=1.[ClH:26]>CO>[ClH:26].[ClH:26].[ClH:26].[N:19]1([CH2:18][C:16]2[CH:15]=[CH:14][N:13]=[C:12]([O:11][CH2:10][CH2:9][CH2:8][NH:7][C:6](=[NH:5])[C:2](=[NH:1])[NH2:3])[CH:17]=2)[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 159613413-Amino-4-[3-(4-piperidinomethyl-2-pyridyloxy)propylamino]-1,2,5-thiadiazole 1-oxide

Product 1

HCID 178478602HCID 178478602, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product of Step B (5.0 g; 13.7 mmoles) was dissolved in 80 ml of methanol and treated with 9.1 ml of concentrated HCl. After stirring at ambient temperature for 4.5 hours, the solution was evaporated to dryness under reduced pressure to give the title compound.

Workup

  1. customthe solution was evaporated to dryness under reduced pressure

Sources & evidence

ORD record
ord-34efabebc5f249608df08f2ef342b18a
Source dataset
uspto-grants-1986_05
Patent number
US04588826

Reaction notes

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