Benzyl Chloride → 2-(2'-Benzylthio-5'-chlorophenyl)-imidazolidine hydrochloride

HRID 280428Notes

Reaction equation

HRID 280428 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[S:13][C:8]3([NH:12][CH2:11][CH2:10][NH:9]3)[C:6]=2[CH:7]=1.[CH2:14](Cl)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>CO>[ClH:1].[CH2:14]([S:13][C:5]1[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][C:6]=1[CH:8]1[NH:12][CH2:11][CH2:10][NH:9]1)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

4

Reactant 2

HCID 7503Benzyl ChlorideHCID 704691194-Chlorobenzothietane-2-spiro-2'-imidazoline

Product 1

HCID 233204192-(2'-Benzylthio-5'-chlorophenyl)-imidazolidine hydrochloride

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

32 parts of 4-chlorobenzothietane-2spiro-2'-imidazolidine is reacted with 19 parts of benzyl chloride in 300 parts of methanol as described in Example 11. The yield is 43 parts (84% of theory) and the melting point is 260° C. with decomposition.

Sources & evidence

ORD record
ord-3d368d9093da4335bf537a9da68c0272
Source dataset
uspto-grants-1986_05
Patent number
USRE032154

Reaction notes

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