Diethyl Ether → HCID 54258967, compound

Participants

Reaction Steps

6.1 parts of N-methoxy-N-methylamine were added to a solution of 26.8 parts of 5-(4'-isocyanatophenoxy)-benzisothiazole in 300 parts of diethyl ether at from 20° to 30° C., the mixture was stirred for 12 hours at this temperature and then evaporated down, and the residue was triturated in about 50 parts of diethyl ether, isolated and dried. 26 g (82% of theory) of 5-(4'-(N-methoxy-N-methylaminocarbonylamino)-phenoxy)-benzisothiazole of melting point 108° C. were obtained.

Provenance & Evidence