Hydrochloric Acid → 2-Amino-N-[(4-methoxy-6-methyl-2-pyrimidinyl)aminocarbonyl]benzenesulfonamide-Hydrochloride

HRID 28052Notes

Reaction equation

HRID 28052 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([NH:11][C:12]([NH:14][C:15]1[N:20]=[C:19]([O:21][CH3:22])[CH:18]=[C:17]([CH3:23])[N:16]=1)=[O:13])(=[O:10])=[O:9].[ClH:24]>>[ClH:24].[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([NH:11][C:12]([NH:14][C:15]1[N:20]=[C:19]([O:21][CH3:22])[CH:18]=[C:17]([CH3:23])[N:16]=1)=[O:13])(=[O:10])=[O:9]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 131382142-Amino-N-[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]benzenesulfonamide

Product 1

HCID 233383952-Amino-N-[(4-methoxy-6-methyl-2-pyrimidinyl)aminocarbonyl]benzenesulfonamide-Hydrochloride

Procedure

A suspension of 56 mg of 2-amino-N-[(4-methoxy-6-methyl-2-pyrimidinyl)aminocarbonyl]benzenesulfonamide in 5 ml of ethanolic HCl was gently heated on a steam bath for 5 minutes. The resulting white suspension was evaporated in vacuo to yield the hydrochloride m.p. 154-155 (dec.).

Workup

  1. temperaturewas gently heated on a steam bath for 5 minutes
  2. customThe resulting white suspension was evaporated in vacuo

Sources & evidence

ORD record
ord-41f134f4a569404e9f8323eace01fe5e
Source dataset
uspto-grants-1980_09
Patent number
US04225337

Reaction notes

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