Hydrochloric Acid → HCID 86740809, compound

Participants

Reaction Steps

A mixture of 1 g of (±)-cis-2-(4-methoxyphenyl)-3-hydroxy-5-[2-(dimethylamino)ethyl]-9-fluoro-2,3-dihydro-1,5-benzothiazepin-4(5H)-one and 10 ml of acetic anhydride is treated in the same manner as described in Example 54. The crude product is converted to its hydrochloride and recrystallized from a mixture of isopropanol and ether. 0.729 g of (±)-cis-2-(4-methoxyphenyl)-3-acetoxy-5-[2-(dimethylamino)ethyl]-9-fluoro-2,3-dihydro-1,5-benzothiazepin-4(5H)-one hydrochloride is obtained.

Provenance & Evidence