HCID 13376232, compound → Methyl 5-(2-chloroethoxy)thiophene-2-carboxylate

HRID 280566Notes

Reaction equation

HRID 280566 reaction equation
[CH3:1][O:2][C:3]([C:5]1[S:6][C:7]([O:11][CH2:12][CH2:13][Cl:14])=[CH:8][C:9]=1C)=[O:4].COC(C1SC(OCCCl)=C(C)C=1)=O>CO.O>[CH3:1][O:2][C:3]([C:5]1[S:6][C:7]([O:11][CH2:12][CH2:13][Cl:14])=[CH:8][CH:9]=1)=[O:4]

Participants

4

Reactant 2

HCID 13376232HCID 13376232, compoundHCID 13376233HCID 13376233, compound

Product 1

HCID 13376214Methyl 5-(2-chloroethoxy)thiophene-2-carboxylate

Reagents, catalysts & solvents 1

HCID 22242641Methanol--water (1/1)Solvent

Procedure

3-Methyl-5-(2-chloro-1-ethoxy)-thiophene-2-carboxylic acid methyl ester, melting point (MeOH/H2O) 47°-50° C. (86%), and 4-Methyl-5-(2-chloro-1-ethoxy)-thiophene-2-carboxylic acid methyl ester, melting point (petroleum ether) 75° C. (90%).

Sources & evidence

ORD record
ord-21a809119f2244478caf18869078af01
Source dataset
uspto-grants-1986_05
Patent number
US04590203

Reaction notes

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