HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Anisoyl chloride → HCID 13025589, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Anisoyl chloride | HCID 7477 | — |
| Reactant | 3-(Piperazin-1-yl)isoquinoline | HCID 13025569 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 13025589 | HCID 13025589 | — |
Reaction Steps
9.38 g of 4-methoxybenzoyl chloride are added dropwise to 10 g of 3-(piperazin-1-yl)-isoquinoline, dissolved in 40 ml of pyridine. After stirring for 1 hour at room temperature, the mixture is diluted with water and extracted with ethyl acetate. The ethyl acetate phase is dried and the solvent is removed by evaporation. 5.8 g, melting point 156°-159° C., can be isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04590273 |
| Source dataset | uspto-grants-1986_05 |
| ORD ID | ord-c532801cfad04e9a940b085c82fe7225 |
| Source note | uspto-grants-1986_05 |