Glyoxylic Acid → (3-Chloro-4-hydroxyphenyl)(hydroxy)acetic acid

HRID 280722Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[OH:8].[C:9]([OH:13])(=[O:12])[CH:10]=[O:11]>>[Cl:1][C:2]1[CH:7]=[C:6]([CH:5]=[CH:4][C:3]=1[OH:8])[CH:10]([OH:11])[C:9]([OH:13])=[O:12]

Participants

Reactant 2

HCID 760Glyoxylic Acid

HCID 72452-Chlorophenol

Product 1

HCID 3018322(3-Chloro-4-hydroxyphenyl)(hydroxy)acetic acid

Procedure

o-chlorophenol is reacted with glyoxylic acid to give 3-chloro-4-hydroxymandelic acid,

Sources & evidence

ORD record: ord-96b10a351f4c43c4bfd8cb6bb3f75a66
Source dataset: uspto-grants-1986_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04590295

Reaction notes

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