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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 280726Generated: October 26, 2026

Benzene, 1,3-dichloro-2-fluoro-5-(trifluoromethyl)- → Benzene, 1-chloro-2,3-difluoro-5-(trifluoromethyl)-

https://huagongshe.com/reaction/280726

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1,3-dichloro-2-fluoro-5-(trifluoromethyl)-HCID 157026—
Reactant3,5-Dichloro-4-fluorobenzonitrileHCID 13643469—
ProductBenzene, 1-chloro-2,3-difluoro-5-(trifluoromethyl)-HCID 2736496—
Product3-Chloro-4,5-difluorobenzonitrileHCID 13643470—

Reaction Steps

reacting the 3,5-dichloro-4-fluorobenzonitrile or 3,5-dichloro-4-fluorobenzotrifluoride compound prepared in step (B) with an alkali metal fluoride to form the corresponding 3-chloro-4,5-difluorobenzonitrile or 3-chloro-4,5-difluorobenzotrifluoride compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04590315
Source datasetuspto-grants-1986_05
ORD IDord-f4f7478280ff41ffbbf34ba809171653
Source noteuspto-grants-1986_05