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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 280730Generated: October 28, 2026

Benzene, 1,3-dichloro-2-fluoro-5-(trifluoromethyl)- → Benzene, 1-chloro-2,3-difluoro-5-(trifluoromethyl)-

https://huagongshe.com/reaction/280730

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1,3-dichloro-2-fluoro-5-(trifluoromethyl)-HCID 157026—
ReactantPotassium FluorideHCID 522689—
ProductBenzene, 1-chloro-2,3-difluoro-5-(trifluoromethyl)-HCID 2736496—

Reaction Steps

reacting the 3,5-dichloro-4-fluorobenzotrifluoride product of step (B) with potassium fluoride in the liquid phase at a temperature of about 170° to about 270° Celsius to form 3-chloro-4,5-difluorobenzotrifluoride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04590315
Source datasetuspto-grants-1986_05
ORD IDord-f6eb4f2577714fa0a6ea6d91fc67f050
Source noteuspto-grants-1986_05