化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → Methyl 4-amino-2-methanesulfonyloxybenzoate hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Methyl 2-[(methanesulfonyl)oxy]-4-nitrobenzoate | HCID 23320160 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | Methyl 4-amino-2-methanesulfonyloxybenzoate hydrochloride | HCID 23320164 | — |
反応手順
Methyl 2-methanesulfonyloxy-4-nitrobenzoate (14 g) and palladium on carbon (0.5 g, 10%) were suspended in 400 ml of acetic acid and hydrochloric acid (5 ml, density 1.18). The suspension was hydrogenated in a Parr hydrogenation apparatus at 250 kPa. The palladium carbon was filtered off, and the solution was evaporated; the crystal mass was washed with ethyl acetate and dried. Yield: 11 g.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04591584 |
| 出典データセット | uspto-grants-1986_05 |
| ORD ID | ord-547ee29b8cc149aa9dffe94f3681d771 |
| 出典メモ | uspto-grants-1986_05 |