反应详情

Methyl 2-methanesulfonyloxy-4-nitrobenzoate (14 g) and palladium on carbon (0.5 g, 10%) were suspended in 400 ml of acetic acid and hydrochloric acid (5 ml, density 1.18). The suspension was hydrogenated in a Parr hydrogenation apparatus at 250 kPa. The palladium carbon was filtered off, and the solution was evaporated; the crystal mass was washed with ethyl acetate and dried. Yield: 11 g.

1. filtrationThe palladium carbon was filtered off
2. customthe solution was evaporated
3. washthe crystal mass was washed with ethyl acetate
4. customdried