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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 28108Generated: October 30, 2026

Formaldehyde → 3-hydroxymethyl-5-(4-pyridinyl)-2(1H)-pyridinone

https://huagongshe.com/reaction/28108

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
Reactant[3,4'-Bipyridin]-6(1H)-oneHCID 13289548—
Product3-hydroxymethyl-5-(4-pyridinyl)-2(1H)-pyridinoneHCID 20517044—

Reaction Steps

The process which comprises reacting 5-(4-pyridinyl)-2(1H)-pyridinone with excess formaldehyde at an acidic pH to produce 3-hydroxymethyl-5-(4-pyridinyl)-2(1H)-pyridinone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04225601
Source datasetuspto-grants-1980_09
ORD IDord-4be1b036d75c41e885340180cf860be5
Source noteuspto-grants-1980_09