HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1-Dichloroethane → Butanoic acid, 4-oxo-4-((4-phenyl-2-thiazolyl)amino)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1-Dichloroethane | HCID 6365 | — |
| Reactant | Succinic anhydride | HCID 7922 | — |
| Reactant | 2-Amino-4-phenylthiazole | HCID 40302 | — |
| Product | Butanoic acid, 4-oxo-4-((4-phenyl-2-thiazolyl)amino)- | HCID 804919 | — |
Reaction Steps
35.2 g of 4-phenyl 2-amino thiazole are dissolved in 350 ml of boiling 1-2 dichloroethane. To this solution add 20 g of succinic anhydride. The amide formed crystallizes; keep under reflux for five hours and filter. By recrystallization from alcohol there are recovered 39 g (70%) of the product of the formula ##STR12##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04225610 |
| Source dataset | uspto-grants-1980_09 |
| ORD ID | ord-7d95e55333d64ff48f56f2c5454550cc |
| Source note | uspto-grants-1980_09 |