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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 281263Generated: October 30, 2026

1-(4-Bromophenyl)-2,2-difluoroethan-1-ol → 2-(4-(2,2-Difluoro-1-hydroxyethyl)phenyl)-8-(3,3-dimethylbutanoyl)-2,8-diazaspiro[4.5]decan-1-one

https://huagongshe.com/reaction/281263

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Bromophenyl)-2,2-difluoroethan-1-olHCID 15942204—
Reactant8-(3,3-Dimethyl-butyryl)-2-[4-(2,2,2-trifluoro-1-hydroxy-ethyl)-phenyl]-2,8-diaza-spiro[4.5]decan-1-oneHCID 59577894—
Reactant8-(3,3-Dimethyl-butyryl)-2,8-diaza-spiro[4.5]decan-1-oneHCID 59578014—
Product2-(4-(2,2-Difluoro-1-hydroxyethyl)phenyl)-8-(3,3-dimethylbutanoyl)-2,8-diazaspiro[4.5]decan-1-oneHCID 59578022—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-ee4e55acfed741b9a1032cb68bbda653
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)