HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 281263Generated: October 30, 2026
1-(4-Bromophenyl)-2,2-difluoroethan-1-ol → 2-(4-(2,2-Difluoro-1-hydroxyethyl)phenyl)-8-(3,3-dimethylbutanoyl)-2,8-diazaspiro[4.5]decan-1-one
https://huagongshe.com/reaction/281263
Participants
| Role | Name | HCID | Charge |
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| Reactant | 1-(4-Bromophenyl)-2,2-difluoroethan-1-ol | HCID 15942204 | — |
| Reactant | 8-(3,3-Dimethyl-butyryl)-2-[4-(2,2,2-trifluoro-1-hydroxy-ethyl)-phenyl]-2,8-diaza-spiro[4.5]decan-1-one | HCID 59577894 | — |
| Reactant | 8-(3,3-Dimethyl-butyryl)-2,8-diaza-spiro[4.5]decan-1-one | HCID 59578014 | — |
| Product | 2-(4-(2,2-Difluoro-1-hydroxyethyl)phenyl)-8-(3,3-dimethylbutanoyl)-2,8-diazaspiro[4.5]decan-1-one | HCID 59578022 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
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| ORD ID | ord-ee4e55acfed741b9a1032cb68bbda653 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
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