HRID281267

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8028

Tetrahydrofuran

C4H8O

HCID10868

Dicyclohexylcarbodiimide

C13H22N2

HCID15381

1-Azabicyclo[2.2.2]octan-3-ol

C7H13NO

HCID75771

1-Hydroxybenzotriazole

C6H5N3O

HCID54890833

未命名化合物

PRODUCTS

生成物

结构：O=C(OC1CN2CCC1CC2)C(Nc1cccc(F)c1)c1ccc(F)cc1

HCID67124838

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-81d5283341274babaa9ca78a51c24f65
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (8/10)

反应 SMILES

[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[CH:39]1([N:40]=[C:41]=[N:42][CH:43]2[CH2:44][CH2:45][CH2:46][CH2:47][CH2:48]2)[CH2:49][CH2:50][CH2:51][CH2:52][CH2:53]1.[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([C:9](=[O:10])[OH:11])[NH:12][c:13]2[cH:14][c:15]([F:19])[cH:16][cH:17][cH:18]2)[cH:6][cH:7]1.[N:20]12[CH2:21][CH:22]([OH:28])[CH:23]([CH2:24][CH2:25]1)[CH2:26][CH2:27]2.[OH:29][n:30]1[c:31]2[c:32]([cH:33][cH:34][cH:35][cH:36]2)[n:37][n:38]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([C:9]([O:10][CH:22]2[CH2:21][N:20]3[CH2:25][CH2:24][CH:23]2[CH2:26][CH2:27]3)=[O:11])[NH:12][c:13]2[cH:14][c:15]([F:19])[cH:16][cH:17][cH:18]2)[cH:6][cH:7]1