Methanol → HCID 178451685, compound

HRID 281416Notes

Reaction equation

HRID 281416 reaction equation
[CH2:1]([O:2][P:3](=[O:4])([O:5][CH2:6][CH3:7])[CH2:9][C:10](=[O:11])[N:12]1[CH2:13][c:14]2[c:15]([c:16]3[c:17]([n:18][cH:19][n:20][c:21]3[NH:22][c:23]3[cH:24][c:25]([Cl:30])[c:26]([F:29])[cH:27][cH:28]3)[s:31]2)[CH2:32][CH2:33]1)[CH3:8].[CH2:52]1[O:53][CH2:54][CH2:55][CH2:56]1.[CH3:50][OH:51].[CH:36](=[O:37])[CH:38]1[N:39]([C:43](=[O:44])[O:45][C:46]([CH3:47])([CH3:48])[CH3:49])[CH2:40][CH2:41][CH2:42]1.[H-:34].[Na+:35]>>[CH:9]([C:10](=[O:11])[N:12]1[CH2:13][c:14]2[c:15]([c:16]3[c:17]([n:18][cH:19][n:20][c:21]3[NH:22][c:23]3[cH:24][c:25]([Cl:30])[c:26]([F:29])[cH:27][cH:28]3)[s:31]2)[CH2:32][CH2:33]1)=[CH:36][CH:38]1[N:39]([C:43](=[O:44])[O:45][C:46]([CH3:47])([CH3:48])[CH3:49])[CH2:40][CH2:41][CH2:42]1

Participants

7

Reactant 6

HCID 887MethanolHCID 923Sodium ionHCID 8028TetrahydrofuranHCID 166653HydrideHCID 42278151-Boc-2-FormylpyrrolidineHCID 58116908Diethyl(2-{4-[(3-chloro-4-fluorophenyl)amino]-5,8-dihydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-7(6H)-yl}-2-oxoethyl)phosphonate

Product 1

HCID 178451685HCID 178451685, compound

Sources & evidence

ORD record
ord-90bef5a7162a43b38e3c75f68476ff33
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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