Dichloromethane → 4-(4-aminophenyl)sulfanyl-N-(1-phenylethyl)-3-[(7-propan-2-ylquinazolin-4-yl)amino]benzamide
Reaction equation
[CH2:54]([Cl:55])[Cl:56].[CH:1]([CH3:2])([CH3:3])[c:4]1[cH:5][cH:6][c:7]2[c:8]([NH:14][c:15]3[c:16]([S:32][c:33]4[cH:34][cH:35][c:36]([NH:39][C:40](=[O:41])[O:42][C:43]([CH3:44])([CH3:45])[CH3:46])[cH:37][cH:38]4)[cH:17][cH:18][c:19]([C:21]([NH:22][CH:23]([CH3:24])[c:25]4[cH:26][cH:27][cH:28][cH:29][cH:30]4)=[O:31])[cH:20]3)[n:9][cH:10][n:11][c:12]2[cH:13]1.[F:47][C:48]([F:49])([F:50])[C:51]([OH:52])=[O:53]>>[CH:1]([CH3:2])([CH3:3])[c:4]1[cH:5][cH:6][c:7]2[c:8]([NH:14][c:15]3[c:16]([S:32][c:33]4[cH:34][cH:35][c:36]([NH2:39])[cH:37][cH:38]4)[cH:17][cH:18][c:19]([C:21]([NH:22][CH:23]([CH3:24])[c:25]4[cH:26][cH:27][cH:28][cH:29][cH:30]4)=[O:31])[cH:20]3)[n:9][cH:10][n:11][c:12]2[cH:13]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-594457fecc8f4ecaa1b4d4c82bb6f051
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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