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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 281622Generated: October 30, 2026

Dimethylformamide → N-(4-Chlorobenzyl)-2-formyl-4-methyl-7-oxo-3-{[2-(trimethylsilyl)ethoxy]methyl}4,7-dihydrothieno[3,2-b]pyridine-6-carboxamide

https://huagongshe.com/reaction/281622

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantDiisopropylamineHCID 7912—
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantDiisopropylamideHCID 5062348—
ReactantN-(4-chlorobenzyl)-4-methyl-7-oxo-3-{[2-(trimethylsilyl)ethoxy]methyl}-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamideHCID 22574323—
ReactantButyllithiumHCID 178418339—
ProductN-(4-Chlorobenzyl)-2-formyl-4-methyl-7-oxo-3-{[2-(trimethylsilyl)ethoxy]methyl}4,7-dihydrothieno[3,2-b]pyridine-6-carboxamideHCID 22574364—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-f02826b68c904b9fa174f25d89775cc1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)