Dimethylformamide → N-(4-Chlorobenzyl)-2-formyl-4-methyl-7-oxo-3-{[2-(trimethylsilyl)ethoxy]methyl}4,7-dihydrothieno[3,2-b]pyridine-6-carboxamide
Reaction equation
[CH2:51]1[CH2:53][CH2:52][CH2:54][O:55]1.[CH3:32][CH:33]([N-:34][CH:35]([CH3:36])[CH3:37])[CH3:38].[CH:39]([NH:40][CH:41]([CH3:42])[CH3:43])([CH3:44])[CH3:45].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][C:8](=[O:9])[c:10]2[c:11](=[O:28])[c:12]3[c:13]([n:14]([CH3:16])[cH:15]2)[c:17]([CH2:20][O:21][CH2:22][CH2:23][Si:24]([CH3:25])([CH3:26])[CH3:27])[cH:18][s:19]3)[cH:29][cH:30]1.[Li+:31].[Li:46][CH2:47][CH2:48][CH2:49][CH3:50].[O:56]=[CH:57][N:58]([CH3:59])[CH3:60]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][C:8](=[O:9])[c:10]2[c:11](=[O:28])[c:12]3[c:13]([n:14]([CH3:16])[cH:15]2)[c:17]([CH2:20][O:21][CH2:22][CH2:23][Si:24]([CH3:25])([CH3:26])[CH3:27])[c:18]([CH:54]=[O:55])[s:19]3)[cH:29][cH:30]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-f02826b68c904b9fa174f25d89775cc1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…