Acetone → N-(3-Fluoro-4-(2-(1-isopropylpiperidin-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-2-(4-fluorophenyl)-3-oxo-2,3-dihydropyridazine-4-carboxamide
Reaction equation
[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH3:41][C:42]([CH3:43])=[O:44].[F:1][c:2]1[cH:3][c:4]([NH:24][C:25](=[O:26])[c:27]2[c:28](=[O:40])[n:29](-[c:33]3[cH:34][cH:35][c:36]([F:39])[cH:37][cH:38]3)[n:30][cH:31][cH:32]2)[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16]([CH:18]1[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]1)[s:17]2>>[F:1][c:2]1[cH:3][c:4]([NH:24][C:25](=[O:26])[c:27]2[c:28](=[O:40])[n:29](-[c:33]3[cH:34][cH:35][c:36]([F:39])[cH:37][cH:38]3)[n:30][cH:31][cH:32]2)[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16]([CH:18]1[CH2:19][CH2:20][N:21]([CH:42]([CH3:41])[CH3:43])[CH2:22][CH2:23]1)[s:17]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-02a41a98587e4e22a9979c8223c0bbed
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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