Trifluoroacetic acid → 2-(cyclohexylmethyl)-5-(3-fluoro-4-hydroxyphenyl)-3-methylpyrimidin-4(3H)-one
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([F:30])[cH:11][c:12](-[c:15]2[c:16](=[O:29])[n:17]([CH3:28])[c:18]([CH2:21][CH:22]3[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]3)[n:19][cH:20]2)[cH:13][cH:14]1.[F:31][C:32]([F:33])([F:34])[C:35]([OH:36])=[O:37]>>[OH:8][c:9]1[c:10]([F:30])[cH:11][c:12](-[c:15]2[c:16](=[O:29])[n:17]([CH3:28])[c:18]([CH2:21][CH:22]3[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]3)[n:19][cH:20]2)[cH:13][cH:14]1Participants
3
Sources & evidence
- ORD record
- ord-2619e3c85b794ccf8385720875eecdba
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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