p-Xylyl bromide → 2-[(4-Methylbenzyl)amino]-1-[3-(trifluoromethyl)phenyl]-1,8-naphthyridin-4(1H)-one
Reaction equation
[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:23][c:24]1[cH:25][cH:26][c:27]([CH2:28][Br:29])[cH:30][cH:31]1.[NH2:1][c:2]1[n:3](-[c:13]2[cH:14][c:15]([C:19]([F:20])([F:21])[F:22])[cH:16][cH:17][cH:18]2)[c:4]2[n:5][cH:6][cH:7][cH:8][c:9]2[c:10](=[O:12])[cH:11]1>>[NH:1]([c:2]1[n:3](-[c:13]2[cH:14][c:15]([C:19]([F:20])([F:21])[F:22])[cH:16][cH:17][cH:18]2)[c:4]2[n:5][cH:6][cH:7][cH:8][c:9]2[c:10](=[O:12])[cH:11]1)[CH2:28][c:27]1[cH:26][cH:25][c:24]([CH3:23])[cH:31][cH:30]1Participants
4
Sources & evidence
- ORD record
- ord-fa907b30b72943aabdffeaf20722a376
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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