Dichloromethane → N-[(4-chlorophenyl)methyl]-6-iodo-7-methoxy-1-methyl-4-oxo-1,8-naphthyridine-3-carboxamide
Reaction equation
[CH2:19]([N:20]([CH2:21][CH3:22])[CH2:23][CH3:24])[CH3:25].[Cl:26][c:27]1[cH:28][cH:29][c:30]([CH2:31][NH2:32])[cH:33][cH:34]1.[Cl:35][CH2:36][Cl:37].[I:1][c:2]1[cH:3][c:4]2[c:5](=[O:18])[c:6]([C:15](=[O:16])[OH:17])[cH:7][n:8]([CH3:14])[c:9]2[n:10][c:11]1[O:12][CH3:13]>>[I:1][c:2]1[cH:3][c:4]2[c:5](=[O:18])[c:6]([C:15](=[O:17])[NH:32][CH2:31][c:30]3[cH:29][cH:28][c:27]([Cl:26])[cH:34][cH:33]3)[cH:7][n:8]([CH3:14])[c:9]2[n:10][c:11]1[O:12][CH3:13]Participants
5
Sources & evidence
- ORD record
- ord-106b0d120e034c1688109454f074040b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…