Hydrochloric Acid → (3RS,4RS,5SR)-4-(4-chloro-phenyl)-3-naphthalen-2-ylmethoxy-5-propyl-piperidine

HRID 281911Notes

Reaction equation

HRID 281911 reaction equation
[CH3:37][OH:38].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH:9]([O:24][CH2:25][c:26]3[cH:27][c:28]4[cH:29][cH:30][cH:31][cH:32][c:33]4[cH:34][cH:35]3)[CH2:10][N:11]([C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[CH2:12][CH:13]2[CH2:14][CH2:15][CH3:16])[cH:6][cH:7]1.[ClH:36]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH:9]([O:24][CH2:25][c:26]3[cH:27][c:28]4[cH:29][cH:30][cH:31][cH:32][c:33]4[cH:34][cH:35]3)[CH2:10][NH:11][CH2:12][CH:13]2[CH2:14][CH2:15][CH3:16])[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 86604425tert-butyl (3RS,4RS,5SR)-4-(4-chloro-phenyl)-3-naphthalen-2-ylmethoxy-5-propyl-piperidine-1-carboxylate

Product 1

HCID 22127569(3RS,4RS,5SR)-4-(4-chloro-phenyl)-3-naphthalen-2-ylmethoxy-5-propyl-piperidine

Sources & evidence

ORD record
ord-4bc5a0085c094e3a98a74473ac721c55
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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