Bicarbonate Ion → tert-Butyl 3-bromo-5-(trifluoroacetyl)benzoate

HRID 281946Notes

Reaction equation

HRID 281946 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[O:7][C:8]([CH3:9])([CH3:10])[CH3:11])[cH:12][c:13]([CH:15]([C:16]([F:17])([F:18])[F:19])[OH:20])[cH:14]1.[Cl:32][CH2:33][Cl:34].[Na+:25].[Na+:30].[Na+:31].[O-:21][C:22]([OH:23])=[O:24].[S:26]([O-:27])([O-:28])=[O:29]>>[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[O:7][C:8]([CH3:9])([CH3:10])[CH3:11])[cH:12][c:13]([C:15]([C:16]([F:17])([F:18])[F:19])=[O:20])[cH:14]1

Participants

6

Reactant 5

HCID 769Bicarbonate IonHCID 923Sodium ion3×HCID 1099SulfiteHCID 6344DichloromethaneHCID 59539580Tert-butyl 3-bromo-5-(2,2,2-trifluoro-1-hydroxyethyl)benzoate

Product 1

HCID 68496903tert-Butyl 3-bromo-5-(trifluoroacetyl)benzoate

Sources & evidence

ORD record
ord-c53dd9f0f16144e1b1fd50b8d98c80a8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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