Sodium ion → 4-{4-[2-(2,5-Dichloro-phenoxy)-5-fluoro-pyridine-3-carbonyl]-3,4-dihydro-2H-quinoxalin-1-yl}-butyric acid ethyl ester

HRID 282008Notes

Reaction equation

HRID 282008 reaction equation
[CH2:31]([CH3:32])[O:33][C:34]([CH2:35][CH2:36][CH2:37][Br:38])=[O:39].[Cl:1][c:2]1[c:3]([O:4][c:5]2[n:6][cH:7][c:8]([F:23])[cH:9][c:10]2[C:11](=[O:12])[N:13]2[CH2:14][CH2:15][NH:16][c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]32)[cH:24][c:25]([Cl:28])[cH:26][cH:27]1.[H-:29].[Na+:30].[O:40]=[CH:41][N:42]([CH3:43])[CH3:44]>>[Cl:1][c:2]1[c:3]([O:4][c:5]2[n:6][cH:7][c:8]([F:23])[cH:9][c:10]2[C:11](=[O:12])[N:13]2[CH2:14][CH2:15][N:16]([CH2:37][CH2:36][CH2:35][C:34]([O:33][CH2:31][CH3:32])=[O:39])[c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]32)[cH:24][c:25]([Cl:28])[cH:26][cH:27]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 76300Ethyl 4-bromobutyrateHCID 166653HydrideHCID 59294514[2-(2,5-Dichloro-phenoxy)-5-fluoro-pyridin-3-yl]-(3,4-dihydro-2H-quinoxalin-1-yl)-methanone

Product 1

HCID 592945484-{4-[2-(2,5-Dichloro-phenoxy)-5-fluoro-pyridine-3-carbonyl]-3,4-dihydro-2H-quinoxalin-1-yl}-butyric acid ethyl ester

Sources & evidence

ORD record
ord-5a2fe0f6058541f1a96403e50c4ed2af
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…