Methanol → HCID 23339566, compound

HRID 28213Notes

Reaction equation

HRID 28213 reaction equation
[Cl:1][C:2]1[CH:12]=[C:11]([CH2:13][CH2:14][CH2:15][CH:16]2[NH:20][C:19](=[O:21])[CH2:18][S:17]2)[CH:10]=[CH:9][C:3]=1[C:4]([O:6][CH2:7][CH3:8])=[O:5].O=C1CSC(C[CH2:29][CH2:30][C:31]2[CH:41]=[CH:40][C:34](C(OCC)=O)=[CH:33][CH:32]=2)N1.CO>C(Cl)(Cl)Cl>[Cl:1][C:2]1[CH:12]=[C:11]([CH2:13][CH2:14][CH2:15][CH:16]2[N:20]([CH2:29][CH2:30][C:31]3[CH2:41][CH2:40][CH2:34][CH2:33][CH:32]=3)[C:19](=[O:21])[CH2:18][S:17]2)[CH:10]=[CH:9][C:3]=1[C:4]([O:6][CH2:7][CH3:8])=[O:5]

Participants

5

Reactant 3

HCID 887MethanolHCID 12866705Ethyl 4-[3-(4-oxo-2-thiazolidinyl)propyl]benzoateHCID 23339577HCID 23339577, compound

Product 1

HCID 23339566HCID 23339566, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

This compound is prepared by the method described in Example 4, Step B, except that an equivalent quantity of ethyl 2-chloro-4-[3-(4-oxo-2-thiazolidinyl)propyl]benzoate is substituted for the ethyl 4-[3-(4-oxo-2-thiazolidinyl)propyl]benzoate of Example 4, Step B. The title compound is obtained as an oil by column chromatography on silica gel with 2% methanol in chloroform as eluant.

Workup

  1. customThis compound is prepared by the method

Sources & evidence

ORD record
ord-1313e4612f0644a38a4617d65665a7c9
Source dataset
uspto-grants-1980_09
Patent number
US04225609

Reaction notes

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