Tetrahydrofuran → 1-(2-(5-Fluoro-2-(methyloxy)-4-pyridinyl)-5-(hydroxymethyl)phenyl)-2,2-dimethyl-1-propanone
Reaction equation
[C:22]([CH3:23])([CH3:24])([CH3:25])[Li:26].[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[F:1][c:2]1[c:3](-[c:10]2[c:11]([C:12]([O:14][CH3:13])=[O:15])[cH:16][c:17]([CH2:20][OH:21])[cH:18][cH:19]2)[cH:4][c:5]([O:8][CH3:9])[n:6][cH:7]1>>[F:1][c:2]1[c:3](-[c:10]2[c:11]([C:12](=[O:14])[C:22]([CH3:23])([CH3:24])[CH3:25])[cH:16][c:17]([CH2:20][OH:21])[cH:18][cH:19]2)[cH:4][c:5]([O:8][CH3:9])[n:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-c1b40a9ed85f45f7928b3bfbc162ebdb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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