Hydrochloric Acid → 3-[1-(2,3-Difluoro-4-methoxyphenyl)tetrazol-5-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine

HRID 282700Notes

Reaction equation

HRID 282700 reaction equation
[ClH:41].[NH2:1][c:2]1[c:3](-[c:26]2[n:27][n:28][n:29][n:30]2-[c:31]2[c:32]([F:40])[c:33]([F:39])[c:34]([O:37][CH3:38])[cH:35][cH:36]2)[cH:4][c:5](-[c:8]2[cH:9][n:10][n:11]([CH:13]3[CH2:14][CH2:15][N:16]([C:19]([O:20][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:25])[CH2:17][CH2:18]3)[cH:12]2)[cH:6][n:7]1.[O:42]1[CH2:43][CH2:44][O:45][CH2:46][CH2:47]1>>[NH2:1][c:2]1[c:3](-[c:26]2[n:27][n:28][n:29][n:30]2-[c:31]2[c:32]([F:40])[c:33]([F:39])[c:34]([O:37][CH3:38])[cH:35][cH:36]2)[cH:4][c:5](-[c:8]2[cH:9][n:10][n:11]([CH:13]3[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]3)[cH:12]2)[cH:6][n:7]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 58293836tert-butyl 4-(4-(6-amino-5-(1-(2,3-difluoro-4-methoxyphenyl)-1H-tetrazol-5-yl)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

Product 1

HCID 252582763-[1-(2,3-Difluoro-4-methoxyphenyl)tetrazol-5-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine

Sources & evidence

ORD record
ord-8b9e69d3eb9f4006b1c1b0716687cc35
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…