Pyrrolidine → HCID 11340957, compound

HRID 282718Notes

Reaction equation

HRID 282718 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([c:7]1[cH:8][c:9]([O:13][c:14]2[c:15]([CH3:32])[cH:16][c:17]([NH:20][c:21]3[c:22]4[c:23]([n:24][cH:25][n:26]3)[cH:27][n:28][c:29]([F:31])[cH:30]4)[cH:18][cH:19]2)[cH:10][cH:11][cH:12]1)=[O:33].[CH2:34]1[CH2:35][CH2:36][NH:37][CH2:38]1.[CH:39]1([C:40]([N:41]2[CH2:42][CH2:43][CH:44]([O:45][c:46]3[cH:47][cH:48][c:49]([NH:50][c:51]4[c:52]5[cH:53][c:54]([N:55]6[CH2:56][CH2:57][CH2:58][CH2:59]6)[n:60][cH:61][c:62]5[n:63][cH:64][n:65]4)[cH:66][c:67]3[CH3:68])[CH2:69][CH2:70]2)=[O:71])[CH2:72][CH2:73][CH2:74][CH2:75]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([c:7]1[cH:8][c:9]([O:13][c:14]2[c:15]([CH3:32])[cH:16][c:17]([NH:20][c:21]3[c:22]4[c:23]([n:24][cH:25][n:26]3)[cH:27][n:28][c:29]([N:37]3[CH2:36][CH2:35][CH2:34][CH2:38]3)[cH:30]4)[cH:18][cH:19]2)[cH:10][cH:11][cH:12]1)=[O:33]

Participants

4

Reactant 3

HCID 31268PyrrolidineHCID 11202845Cyclopentyl-{4-[2-methyl-4-(6-pyrrolidin-1-yl-pyrido[3,4-d]pyrimidin-4-ylamino)-phenoxy]-piperidin-1-yl}-methanoneHCID 69054647HCID 69054647, compound

Product 1

HCID 11340957HCID 11340957, compound

Sources & evidence

ORD record
ord-4dbec71784064f99bb7552b5b8fbaeb5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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