Dichloromethane → 3-Methanesulfonyloxy-1-[4-(thiophene-2-carbonyl-amino)methyl-1,3-thiazol-2-yl]azetidine
Reaction equation
[CH2:32]([Cl:33])[Cl:34].[CH3:20][S:21]([Cl:22])(=[O:23])=[O:24].[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[OH:1][CH:2]1[CH2:3][N:4]([c:6]2[s:7][cH:8][c:9]([CH2:11][NH:12][C:13](=[O:14])[c:15]3[s:16][cH:17][cH:18][cH:19]3)[n:10]2)[CH2:5]1>>[O:1]([CH:2]1[CH2:3][N:4]([c:6]2[s:7][cH:8][c:9]([CH2:11][NH:12][C:13](=[O:14])[c:15]3[s:16][cH:17][cH:18][cH:19]3)[n:10]2)[CH2:5]1)[S:21]([CH3:20])(=[O:23])=[O:24]Participants
5
Sources & evidence
- ORD record
- ord-30598a0f22984639b4cdd2d9cf649bf7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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