Tetrahydrofuran → 8-[5-[(Dimethylamino)methyl]-2-pyridinyl]-1,4-dioxaspiro[4.5]decan-8-ol
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][N:9]([CH3:10])[CH3:11])[cH:6][n:7]1.[CH2:12]([Li:13])[CH2:14][CH2:15][CH3:16].[CH2:17]1[CH2:18][O:19][C:20]2([CH2:21][CH2:22][C:23](=[O:26])[CH2:24][CH2:25]2)[O:27]1.[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1>>[c:2]1([C:23]2([OH:26])[CH2:22][CH2:21][C:20]3([O:19][CH2:18][CH2:17][O:27]3)[CH2:25][CH2:24]2)[cH:3][cH:4][c:5]([CH2:8][N:9]([CH3:10])[CH3:11])[cH:6][n:7]1Participants
5
Sources & evidence
- ORD record
- ord-dc55b84ac31e45058c669d185c7de44e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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