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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 283426Generated: October 30, 2026

1,4-Dioxane → (3,5-Bis-trifluoromethyl-benzyl)-(5-bromopyrimidin-2-yl)-amine

https://huagongshe.com/reaction/283426

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DioxaneHCID 31275—
ReactantDiisopropylethylamineHCID 81531—
Reactant3,5-Bis(trifluoromethyl)benzylamineHCID 521099—
Reactant5-Bromo-2-chloropyrimidineHCID 606665—
Product(3,5-Bis-trifluoromethyl-benzyl)-(5-bromopyrimidin-2-yl)-amineHCID 57551007—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-aed74acb837a419588e1a9e63ff98ec5
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)