1,4-Dioxane → (3,5-Bis-trifluoromethyl-benzyl)-(5-bromopyrimidin-2-yl)-amine
Reaction equation
[Br:17][c:18]1[cH:19][n:20][c:21]([Cl:24])[n:22][cH:23]1.[CH2:34]1[O:35][CH2:36][CH2:37][O:38][CH2:39]1.[CH:25]([N:26]([CH2:27][CH3:28])[CH:29]([CH3:30])[CH3:31])([CH3:32])[CH3:33].[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][NH2:7])[cH:8][c:9]([C:11]([F:12])([F:13])[F:14])[cH:10]1)([F:15])[F:16]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][NH:7][c:21]2[n:20][cH:19][c:18]([Br:17])[cH:23][n:22]2)[cH:8][c:9]([C:11]([F:12])([F:13])[F:14])[cH:10]1)([F:15])[F:16]Participants
5
Sources & evidence
- ORD record
- ord-aed74acb837a419588e1a9e63ff98ec5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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