Dichloromethane → N-(cis-4-cyanocyclohexyl)-N-methyl-[2,1,3]-benzoxadiazole-5-carboxamide

HRID 283438Notes

Reaction equation

HRID 283438 reaction equation
[CH3:1][N:2]([C:3]([O:4][C:5]([CH3:6])([CH3:7])[CH3:8])=[O:9])[CH:10]1[CH2:11][CH2:12][CH:13]([C:16]#[N:17])[CH2:14][CH2:15]1.[Cl:37][CH2:38][Cl:39].[OH:18][C:19]([C:20]([F:21])([F:22])[F:23])=[O:24].[n:25]1[o:26][n:27][c:28]2[c:29]1[cH:30][cH:31][c:32]([C:34]([Cl:35])=[O:36])[cH:33]2>>[CH3:1][N:2]([C:3](=[O:9])[c:32]1[cH:31][cH:30][c:29]2[n:25][o:26][n:27][c:28]2[cH:33]1)[CH:10]1[CH2:11][CH2:12][CH:13]([C:16]#[N:17])[CH2:14][CH2:15]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 27354532,1,3-Benzoxadiazole-5-carbonyl chlorideHCID 66725780t-Butyl methyl-(4-cyanocyclohexyl)carbamate

Product 1

HCID 25104044N-(cis-4-cyanocyclohexyl)-N-methyl-[2,1,3]-benzoxadiazole-5-carboxamide

Sources & evidence

ORD record
ord-765a686d123d44f8ba635fcead5e65cd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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