Methanol → 6-cyclohexyl-4H-thieno[3,2-b]pyrrole-2-carboxylic acid

HRID 283519Notes

Reaction equation

HRID 283519 reaction equation
[C+4:25].[C:1]1([c:7]2[c:8]3[c:9]([nH:10][cH:11]2)[cH:12][c:13]([C:15](=[O:16])[OH:17])[s:14]3)=[CH:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[CH3:18][OH:19].[O:20]1[CH2:21][CH2:22][CH2:23][CH2:24]1.[OH-:26].[OH-:28].[OH-:29].[OH-:30].[OH-:31].[OH-:32].[Pd+2:27]>>[CH:1]1([c:7]2[c:8]3[c:9]([nH:10][cH:11]2)[cH:12][c:13]([C:15](=[O:16])[OH:17])[s:14]3)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

7

Reactant 6

HCID 887MethanolHCID 961Hydroxide6×HCID 8028TetrahydrofuranHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 586790836-(cyclohex-1-enyl)-4H-thieno[3,2-b]pyrrole-2-carboxylic acidHCID 178420935HCID 178420935, compound

Product 1

HCID 586790966-cyclohexyl-4H-thieno[3,2-b]pyrrole-2-carboxylic acid

Sources & evidence

ORD record
ord-4ca1162c680049e78a01eb2f2cd91141
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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