Tetrahydrofuran → 2-[2-Fluoro-4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]-9-oxa-2-azaspiro[5.5]undecan-1-one
Reaction equation
[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[CH3:1][O:2][C:3](=[O:4])[C:5]1([CH2:11][CH2:12][CH2:13][NH:14][c:15]2[c:16]([F:32])[cH:17][c:18]([N:21]3[CH2:22][CH:23]([N:26]4[CH:27]([CH3:31])[CH2:28][CH2:29][CH2:30]4)[CH2:24][CH2:25]3)[cH:19][cH:20]2)[CH2:6][CH2:7][O:8][CH2:9][CH2:10]1.[CH3:33][CH2:34][CH2:35][CH2:36][Li:37]>>[O:2]=[C:3]1[C:5]2([CH2:6][CH2:7][O:8][CH2:9][CH2:10]2)[CH2:11][CH2:12][CH2:13][N:14]1[c:15]1[c:16]([F:32])[cH:17][c:18]([N:21]2[CH2:22][CH:23]([N:26]3[CH:27]([CH3:31])[CH2:28][CH2:29][CH2:30]3)[CH2:24][CH2:25]2)[cH:19][cH:20]1Participants
4
Sources & evidence
- ORD record
- ord-5c13cadac3f04d979321a74548203a2b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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