Acetate → 2,4-Dimethoxy-5-o-tolyl-pyrimidine

HRID 283618Notes

Reaction equation

HRID 283618 reaction equation
[C:22](=[O:23])([O-:24])[O-:25].[CH3:12][c:13]1[c:14]([B:19]([OH:20])[OH:21])[cH:15][cH:16][cH:17][cH:18]1.[I:1][c:2]1[c:3]([O:10][CH3:11])[n:4][c:5]([O:8][CH3:9])[n:6][cH:7]1.[Na+:26].[Na+:27].[O-:48][C:49]([CH3:50])=[O:51].[O-:52][C:53]([CH3:54])=[O:55].[Pd+2:47].[c:28]1([P:29]([c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)[cH:42][cH:43][cH:44][cH:45][cH:46]1>>[c:2]1(-[c:14]2[c:13]([CH3:12])[cH:18][cH:17][cH:16][cH:15]2)[c:3]([O:10][CH3:11])[n:4][c:5]([O:8][CH3:9])[n:6][cH:7]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 923Sodium ion2×HCID 11776TriphenylphosphineHCID 19660Carbonate IonHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 2634165-Iodo-2,4-dimethoxypyrimidineHCID 27332672-Methylphenyl boronic acid

Product 1

HCID 398263862,4-Dimethoxy-5-o-tolyl-pyrimidine

Sources & evidence

ORD record
ord-f0dc014dadc24c2ba26e13117828a7e4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…