Ammonia → N-(2,6-difluorophenyl)-3-{3-[2-({2-(methyloxy)-4-[4-(methylsulfonyl)-1-piperazinyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Reaction equation
[CH3:34][O:35][c:36]1[c:37]([NH2:38])[cH:39][cH:40][c:41]([N:43]2[CH2:44][CH2:45][N:46]([S:49](=[O:50])(=[O:51])[CH3:52])[CH2:47][CH2:48]2)[cH:42]1.[CH3:71][OH:72].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:17]3[cH:18][c:19]([C:20](=[O:21])[NH:22][c:23]4[c:24]([F:30])[cH:25][cH:26][cH:27][c:28]4[F:29])[cH:31][cH:32][cH:33]3)[n:10][c:11]3[n:12]2[cH:13][cH:14][cH:15][cH:16]3)[n:7]1.[Cl:73][CH2:74][Cl:75].[F:64][CH2:65][C:66]([F:67])([F:68])[OH:69].[NH3:70].[c:53]1([CH3:54])[cH:55][cH:56][c:57]([S:58]([OH:59])(=[O:60])=[O:61])[cH:62][cH:63]1>>[c:2]1([NH:38][c:37]2[c:36]([O:35][CH3:34])[cH:42][c:41]([N:43]3[CH2:44][CH2:45][N:46]([S:49](=[O:50])(=[O:51])[CH3:52])[CH2:47][CH2:48]3)[cH:40][cH:39]2)[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:17]3[cH:18][c:19]([C:20](=[O:21])[NH:22][c:23]4[c:24]([F:30])[cH:25][cH:26][cH:27][c:28]4[F:29])[cH:31][cH:32][cH:33]3)[n:10][c:11]3[n:12]2[cH:13][cH:14][cH:15][cH:16]3)[n:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-d407644f0276402e97ed6ed8efeca308
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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